Apathy, Novelty Processing, and the P3 Potential in Parkinson’s Disease
نویسندگان
چکیده
منابع مشابه
Apathy, Novelty Processing, and the P3 Potential in Parkinson’s Disease
Parkinson's disease (PD) is characterized by deficits in goal-directed behavior as well as mood and motivational symptoms, including apathy, depression, and anxiety. The present study investigated novelty processing in PD, using event-related potentials (ERPs) to characterize electrophysiological reflections of visual novelty processing. Since apathy has been associated with decreased novelty p...
متن کاملReinstating the Novelty P3
P300 (or P3) is a major positive complex in the human event-related potential, occurring some 300 ms after stimulus onset, and long thought to be the cortical correlate of the Orienting Reflex, our automatic attention-grabbing response to a novel stimulus. The Novelty P3 was the third P3 subcomponent discovered (after P3a and P3b) and appeared promising in its sensitivity to stimulus novelty, t...
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BACKGROUND AND PURPOSE Apathy is associated with decreased novelty-seeking behaviors and is a prevailing behavioral symptom after stroke affecting cortical and subcortical regions. We studied the relationship between apathetic state after subcortical stroke and neural orienting response to novel events using an event-related evoked potential (ERP) technique. METHODS Twenty-nine patients with ...
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Parkinson's disease is associated with emotional changes including depression, apathy, and anxiety. The current study investigated emotional processing in non-demented individuals with Parkinson disease (PD) using an electrophysiological measure, the centro-parietal late positive potential (LPP). Non-demented patients with Parkinson's disease (n=17) and healthy control participants (n=16) viewe...
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It has been proposed that the functional role of the mismatch negativity (MMN) generating process is to issue a call for focal attention toward any auditory change violating the preceding acoustic regularity. This paper reviews the evidence supporting such a functional role and outlines a model of how the attentional system controls the flow of bottom-up auditory information with regard to ongo...
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ژورنال
عنوان ژورنال: Frontiers in Neurology
سال: 2016
ISSN: 1664-2295
DOI: 10.3389/fneur.2016.00095